A Fatality Related to Two Novel Hallucinogenic Compounds: 4-Methoxyphencyclidine and 4-Hydroxy-N-methyl-N-ethyltryptamine
نویسندگان
چکیده
منابع مشابه
Hepatic metabolism of N-hydroxy-N-methyl-4-aminoazobenzene and other N-hydroxy arylamines to reactive sulfuric acid esters.
Hepatic cytosols catalyzed a 3'-phosphoadenosine 5'-phosphosulfate (PAPS)-dependent O-sulfonation of N-hydroxy-N-methyl-4-aminoazobenzene (N-HO-MAB) and of several other N-hydroxy arylamines. The presumed product from N-HO-MAB, N-methyl-4-aminoazobenzene-N-sulfate, reacted with added guanosine to yield N-(guanosin-8-yl)-N-methyl-4-aminoazobenzene, with methionine to form a sulfonium derivative ...
متن کاملN-(4-Fluorobenzoyl)-2-hydroxy-4-methylbenzohydrazide
In the title compound, C(15)H(13)FN(2)O(3), the aromatic rings are aligned at an angle of 10.15 (3)°. The mol-ecules are packed with π-π stacking inter-actions [mean inter-planar distances of 3.339 (2) and 3.357 (3) Å] and the crystal structure is stabilized by inter-molecular N-H⋯O and O-H⋯O hydrogen bonds. An intramolecular N-H⋯O interaction also occurs.
متن کامل4-Methyl-N-phenylbenzenesulfonamide
In the title compound, C(13)H(13)NO(2)S, the dihedral angle between the aromatic rings is 68.4 (1)°. In the crystal, the molecules are linked into inversion dimers by pairs of N-H⋯O hydrogen bonds. The unit cell of this compound was reported previously [Oh et al. (1985 ▶). Chung. Kwa. Yong. (Chung. J. Sci.), 12, 67] but no atomic coordinates were established in the earlier study.
متن کاملPharmacological characterization of Ro 63-1908 (1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol), a novel subtype-selective N-methyl-D-aspartate antagonist.
Ro 63-1908, 1-[2-(4-hydroxy-phenoxy)-ethyl]-4-(4-methyl-benzyl)-piperidin-4-ol, is a novel subtype-selective N-methyl-D-aspartate (NMDA) antagonist that has been characterized in vitro and in vivo. Ro 63-1908 inhibited [(3)H]dizocilpine ((3)H-MK-801) binding in a biphasic manner with IC(50) values of 0.002 and 97 microM for the high- and low-affinity sites, respectively. Ro 63-1908 selectively ...
متن کامل6-Chloro-N 4-methyl-N 4-phenylpyrimidine-4,5-diamine
In the title compound, C(11)H(11)ClN(4), the dihedral angle between the aromatic rings is 66.47 (8)°. In the crystal, mol-ecules are linked by N-H⋯N hydrogen bonds, generating C(5) chains propagating in [010]. Slipped aromatic π-π stacking between centrosymmetrically related pairs of pyrim-idine rings also occurs [centroid-centroid separation = 3.7634 (12)Å and slippage = 1.715 Å].
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Analytical Toxicology
سال: 2015
ISSN: 0146-4760,1945-2403
DOI: 10.1093/jat/bkv089